By Anatoli Silajev
January 17, 2022
– homosexual and bisexual men (43%), – heterosexual individuals with drugs taken intravenously (26%), – homosexual and bisexual individuals using drugs intravenously (5%), – heterosexual individuals (10%), – children (1%), – recipients of blood, blood components or transplants (2%), – haemophiliacs (1%), – and people with not determined risk factors (6%).
The ranging of risk groups in most advanced countries is identical:
Research can reveal the presence of the human immunodeficiency virus in the blood within different periods. Viraemia reaches a high 1-12 days after the contamination and lasts until specific antibodies appear (a period of seroconversion). Besides, the analysis of the laboratory data with long-living patients suggests that HIV over different periods (up to 10-15 years) has no symptoms of the disease. Moreover, throughout that period, the body defences suppress pathogen reproduction more or less effectively. However, low doses of cocaine added to the infected mononuclear cell culture intensify HIV replication, possibly on the account.
That mechanism can contribute to the frequency of AIDS development with drug addicts. The incubation usually lasts 2-4 weeks. The symptoms of the Human immunodeficiency virus are similar to those with infectious mononucleosis or a chill. Fever, lymphangitis, a sore throat, myalgia, headache, indisposition and sometimes a maculopapular rash are most common. However, for lack of pathognomonic signs, diagnostic mistakes may result. Some primary manifestations with most patients may disappear.
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However, headaches and adenopathy may linger for a long time. In evidence, fever, excessive overnight perspiration, and headache with no specific or opportunistic infection indicate a symptomless HIV infection. Diarrhoea can probably result from the human immunodeficiency virus contamination of the intestinal mucosa. Kaposi's sarcoma may develop quite early. The dynamics can show energy and give some other laboratory proof of immunodeficiency. Certain concomitant infections tend to arise, especially oral candidiasis, leukoplakia of buccal mucosa, upper and lower respiratory tract infections and periodontium disorders.