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Probiotic bacteria strain – Bacillus subtilis 60 mg
Bacillus subtilis is a specific, clinically tested and patented strain of probiotic bacteria. Firstly, it improves natural defences. Secondly, it helps in fighting infection and external aggressions. Also, these probiotic strains with solid resistance to acidity
- have anti-bacterial and anti-fungal effects;
- may reduce the growth of pathogenic bacteria.
Therefore, specially selected and studied for its immunostimulant properties, this strain is listed in the Collection Nationale française de cultures de microorganisms (CNCM) as no. I-2745. Pre-clinical and clinical trials have shown that taking Probiotic bacteria Bacillus subtilis boosts immunity in older people significantly. As a result, it protects them from winter infections in particular. Unlike some other strains, these high-quality probiotic bacteria are spore-forming. For instance, it creates cells that are particularly thermo-resistant, offering many advantages:
- increased efficacy in the intestines precisely where microflora is, due to very high resistance during passage through the digestive tract;
- increased stability in the capsule at ambient temperatures (DRcaps™);
- the high survival rate in the GI tract and the ability to activate IgA-producing cells (immunoglobulin A is a crucial immunity antibody) demonstrated in vitro and in vivo in pre-clinical tests and a clinical trial in France.
What do studies show about Bacillus Subtilis?
Pre-clinical and clinical trials have shown that taking Bacillus subtilis boosts immunity in older people and protects them from winter infections in particular. Besides, this double-blind clinical trial involved 44 subjects aged 60 and over. So, they took 20mg of Bacillus Subtilis ten days per month for four months during winter.
Further, results showed vast improvements. Firstly, a significant increase (vs placebo) in IgA concentrations in the respiratory and intestinal mucosa (saliva and stools) occurred. Secondly, a significant decrease (-38%) in the number of days with infectious episodes and a reduced likelihood of reporting infectious incidents.
Because of these factors, we recommend using probiotic bacteria Bacillus subtilis freely by adults. Especially older individuals whose immune systems are under particular stress may need a boost as winter approaches can take it. Besides, people can take this supplement in conjunction with vitamin D3, vitamin C and zinc. In short, all of those have recognised immunostimulant properties.
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Composition of probiotic Bacillus subtilis
| Daily dose: 1 capsule Number of doses per pack: 60 | Amount per dose |
| LifeinU™ Bacillus subtilis CU1 | 60 mg (3.109CFU) |
|
Other ingredients Acacia gum, white rice bran. Probisis®, Lesaffre, France. |
Directions for use
Adults. Take one capsule a day. Keep refrigerated.
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Researchers found the bacteria Bacillus subtilis and Bacillus licheniformis initially in the soil in Siberia's ecologically clean region. Then researchers derived the new strains by modifying them with plasmid pBMB 105, which can produce interferon 2-alpha-leukocyte in humans.
Activities
Being a factor of nonspecific resistance of the body, it plays a controlling and regulatory role in maintaining the homeostasis in the human body and has the following main activities:
- antiviral effect;
- suppresses the growth and development of intracellular infectious agents of a non-viral nature (chlamydia, rickettsia, bacteria, protozoa);
- antiproliferative activity;
- antitumorigenic and antimutagenic effect;
- antitoxic action;
- radioprotective effect;
- stimulates macrophages and enhances phagocytosis;
- enhances the cytotoxic effect of sensitised lymphocytes on target cells;
- increases the formation of surface antigens;
- enhances or inhibits the activity of many cellular enzymes;
- enhances the cytotoxic effect of double-stranded RNA
- suppresses or enhances the production of antibodies;
- activates natural killer cells;
- stimulates the release of histamine by basophils;
- increases the synthesis of prostaglandins;
- enhances the formation of histocompatibility antigens;
- suppresses delayed-type hypersensitivity.
Bacillus subtilis and Bacillus licheniformis bacteria as constituents of healthy microflora
To clarify, Bacillus subtilis bacteria and Bacillus licheniformis are not normal flora in microbial communities of humans and animals. In other words, they possess properties that enable the body to maintain microbicides at ecologically natural levels. Those properties optimise metabolism. They also supply the organism with biologically active and building substances, ensuring qualitative digestion of food. These species' bacteria have always come from the environment into the gastrointestinal tract (GIT), the skin in the physical conditions. Currently, more than 3000 species of these bacteria are known.
Bacteria Bacillus subtilis and Bacillus licheniformis live in the digestive tract after entering for no more than 30 days, and after that, they leave the body naturally. This species' bacteria do not die in the stomach because it is highly resistant to gastric juice's effects in spore form.
Effect
They transform into a vegetative form in the mouth and the small and large parts of the intestine. They also multiply there and produce biologically active substances into the environment. It also affects the growth and development of putrefactive, pathogenic and opportunistic microflora, E. coli. Moreover, other microorganisms restore providing the normal functioning of the microflora of the gastrointestinal tract.
The ability to suppress the growth and development of microflora of the above types of bacterias is made mainly by producing polyene antibiotics like bacitracin and licheniformins. Also, they indirectly optimise the functioning of the human and animal immune systems.
Irrigation of the intestine in our London clinic helps to normalise the microflora of the colon. Doing that, we also prepare the best environment for probiotics. It may also help restore the body's immune system properties.
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