Postcoital test after washing the vagina with sodium bicarbonate. In a sample of 55 patients. Whose postcoital tests were unsatisfactory or contrary, underwent vaginal washing with sodium bicarbonate. Increasing the pH of the cervix made the test positive in 30% of cases, and three pregnancies occurred. Vaginal flushing treatment with sodium bicarbonate has proven to be useful and convenient for patients.
The study aimed to evaluate the effect of vaginal washing with sodium bicarbonate on the viscoelasticity of the cervical mucosa and the penetration of sperm in vitro and in vivo. The study involved 25 couples with primary infertility for more than 12 months. Selection criteria: sperm quality consistent with the concept, regular ovulatory cycles and repeated negative results of the postcoital test (PCT).
There were studies of three consecutive periods after at least one inventory cycle. Researchers used either 1.5% sodium bicarbonate or 0.9% sodium chloride for vaginal douching in the second and third cycles.
A group of scientists of University Hospital Nijmegen in the Netherlands studied the viscoelasticity of the mucous membrane of the cervix uteri. They also carried out tests for the penetration of semen (PPP) and PCT. Viscoelasticity of mucus samples after irrigation with sodium bicarbonate was significantly lower than the viscosity after irrigation with sodium chloride (P less than 0.001, n = 16) and in control cycles (P = 0.003). SPT was significantly higher in sodium bicarbonate cycles than in sodium chloride cycles (P = 0.004, n = 22) and in control cycles (P less than 0.001). PCT values were significantly higher after irrigation with sodium bicarbonate than after irrigation with sodium chloride (P = 0.002, n = 21).
Comparison of sodium bicarbonate and control cycles also showed a significant improvement in PCT evaluation after irrigation with sodium bicarbonate (P <0.001).