Pseudomonas aeruginosa

Anatoli Silajev Comments 0 26th June 2012
Pseudomonas aeruginosa

Pseudomonas aeruginosa is the blue bacillus, the primary pathogen of human infectious disorders. The microorganism can be isolated from the intestines of 5% of healthy people and up to 30% of patients. Besides, bacillus can be everywhere.


It can survive in water for about a year (at 37 °C). Sometimes it is also a part of healthy human microflora. Moreover, it can be on the grain skin, armpit skin and ear skin in healthy individuals (up to 2% of people), on the nasal mucous membrane (about 3%), in the pharynx (about 7%) and the digestive tract (3-24%).


Pseudomonas aeruginosa contamination gives rise to 15-2-% nosocomial infections. Besides, it’s responsible for one-third of all urogenital disorders in urogenital patients. Moreover, it causes 20-25% of purulent surgical infections and primary gram-negative bacteriemia. Patients with burns or bladder disorders, especially those taking antibiotics long enough, are at risk. It is a distinct chemoorganotroph and a strict aerobe.

Clinical manifestations of Pseudomonas aeruginosa

Like other aerobes, it also synthesizes cytochrome oxidase (indophenol oxidase). Pigment formation is a specific sign of great diagnostic importance (with 70-80% clinical isolators)—the phenazine pigment pyocyanine colours the blue-green nutrient medium wound discharge and bandaging material—toxin formation. The pathogenic effect has exotoxin properties. Further, releasing endotoxins leads to the destruction and disintegration of the bacterial cells.

Clinical manifestations for Pseudomonas aeruginosa. High invasiveness is not typical. However, the ubiquitous prevalence of the bacillus makes it the primary pathogen of wound infections and complications. The infections, especially those in hospitals, run a grave course. And septicemia is fatal for 35 to 75% of patients.