Candida auris symptoms

Candida auris is the latest of the Candida genus fungi discovered to date. Besides, as studies show, the most dangerous. Candida auris symptoms are complicated to determine since the infection is poorly studied.

Properties

The main properties of this kind of candidiasis are:

• the ability to quickly enter the bloodstream and impact the internal organs;
• high resistance to all known antifungal medicines (resistance to various groups reaches 30-60%);
• the death rate in case of infection is more than 60%.

The specificity of the fungus’s life outside the organism of the infected patient or carrier of the pathogen is not known. Besides, there were no cases of Candida Auris finding out from clinics and hospitals.

Moreover, pathogens in different countries have differences in structure and pathogenicity; therefore there is an assumption about spontaneous mutations of already existing fungal populations under the influence of external factors, which leads to the appearance of Candida auris. But this theory has not yet been confirmed.

Candida auris symptoms and survival

Candida auris differs from other types of candidiasis infection in its ability to penetrate the bloodstream rapidly. Further, it causes fungal sepsis: the spread of the pathogen to all internal organs.

So, the presence of fungus in the blood leads to Candida auris symptoms:

• Violation of the functions of oxygen delivery to tissues;
• Reduction in nutrient intake;
• All types of body protection get weak.

The pathogen also penetrates the liver, lungs, kidneys, brain and heart from the blood flow system. Reproduction of the fungal population gradually reduces the functional activity of these organs as well as leads to the development of multi-organ failure.

Symptoms

The state of patients’ health quickly turns into an extreme degree of severity, which manifests itself:

• frequent palpitations (> 100-120 per minute);
• a significant reduction in blood pressure (<80 to 40);
• increased respiration (> 25-30 per min);
• a decrease in the amount of urine released (<500-200 ml per day);
• weakness: a person can not even turn in bed;
• a violation of consciousness level: from deafness to coma;
• an increase of renal and hepatic markers in the blood (creatinine, bilirubin);
• the development of diabetes due to impaired pancreatic function.

Death occurs in 60-70% of all cases due to the internal organs’ failure caused by total fungal resistance to the therapy. The time of the pathology development is about one week.

The difficulty in treating a fungal infection caused by Candida Auris is a high degree of insensitivity to all types of antifungal medicines. The fact is that Candida auris symptoms are complex to determine.